Description

Tiacrilast CAS NO 78299-53-3 is a specialized pharmaceutical intermediate and active ingredient with significant therapeutic potential. This compound is valued for its role in the research and development of novel anti-inflammatory and anti-allergic medications. It is primarily sought by pharmaceutical R&D departments and fine chemical manufacturers engaged in the synthesis of advanced drug candidates. The material's specific pharmacological profile makes it a critical component for developing targeted therapies.

Application

• Pharmaceutical Active Ingredient (API): Core component in the formulation of anti-inflammatory and anti-allergic drug products.
• Clinical Research Material: Used in preclinical and clinical studies to investigate efficacy and safety profiles.
• Reference Standard: Serves as a high-purity standard for analytical method development and quality control in regulatory submissions.
• Biochemical Research: Employed in studies targeting specific inflammatory pathways and mediator release.
• Fine Chemical Synthesis: Key building block for the synthesis of more complex, proprietary pharmaceutical compounds.

Basic Information

Item	Detail
Product Name	Tiacrilast
CAS No.	78299-53-3
Molecular Formula	C15H12N2O3S
Molecular Weight	300.33 g/mol
Synonyms	Tiracrilast; 6,7-Dihydro-2-(1H-imidazol-1-ylmethyl)-5H-pyrano[2,3-b]pyridin-5-one; 6,7-Dihydro-2-(imidazol-1-ylmethyl)-5H-pyrano[2,3-b]pyridin-5-one; 5H-Pyrano[2,3-b]pyridin-5-one, 6,7-dihydro-2-(1H-imidazol-1-ylmethyl)-; 6,7-Dihydro-2-(1-imidazolylmethyl)-5H-pyrano[2,3-b]pyridin-5-one; 6,7-Dihydro-2-(imidazol-1-ylmethyl)-5H-pyrano[2,3-b]pyridin-5-one; Tiacrilastum [Latin]; UNII-6J8U2625QO
EINECS	Contact for details

Quality Control

Our Tiacrilast is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes comprehensive analytical testing, including HPLC, IR, and NMR, to confirm identity and potency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting compliance with agreed specifications. We support development and commercial projects requiring material that meets GMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.