Description

Okadaic Acid is a potent polyether toxin and a selective inhibitor of protein phosphatases PP1 and PP2A. This compound is a critical biochemical tool for studying cellular signaling pathways, particularly those involving protein phosphorylation. It is essential for researchers and manufacturers in the fields of biomedical research, pharmacology, and toxicology.

Application

• Biochemical Research: A primary tool for studying signal transduction, cell cycle regulation, and tumor promotion by selectively inhibiting serine/threonine protein phosphatases.
• Pharmaceutical Development: Used in drug discovery programs to investigate and validate targets related to cancer, neurodegenerative diseases, and metabolic disorders.
• Toxicology & Environmental Monitoring: Serves as a reference standard for detecting and quantifying diarrhetic shellfish poisoning (DSP) toxins in seafood safety testing.
• Cell Biology Studies: Employed to induce hyperphosphorylation of proteins in cell culture models to study subsequent physiological effects.
• Diagnostic Kit Production: Used as a calibrant or control in the development of immunoassays and biosensors for marine biotoxins.

Basic Information

Product Name	Okadaic Acid
CAS No.	78111-17-8
Molecular Formula	C44H68O13
Molecular Weight	805.00 g/mol
Synonyms	Okadaic acid; 9,10-Deepithio-9,10-didehydroacanthifolicin; Acanthifolicin, 9,10-deepithio-9,10-didehydro-; OA; NSC 326321; PP1/PP2A Inhibitor; Diarrhetic Shellfish Poison (DSP) Toxin; (2R)-2-Hydroxy-12-[(1S,4R,7S,10S,13R,16S,19R,22S,25S,28S,31S,34R,37S,40S,43S)-4,7,16,19,22,28,31,34,37,40-decamethyl-43-[(2S)-6-methyl-2-[(2S,3S,4R)-3-methyl-4-[(2R,4R,5S,6S)-5-methyl-4,6-dihydro-2H-pyran-2-yl]oxan-2-yl]heptan-2-yl]-1,10,13,25-tetramethyl-3,6,9,12,15,18,21,24,27,30,33,36,39,42-tetradecaoxapentatetracontan-1-yl]dodecanoic acid
EINECS	Contact for details

Quality Control

Our Okadaic Acid is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant standards for reference materials and biochemical reagents.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.