Description

14-Iodo-15-Hydroxyeicosatrienoic Acid, Omega Lactone is a specialized eicosanoid derivative, a key synthetic intermediate and research compound in the study of lipid signaling pathways. Its unique iodinated and lactonized structure makes it a valuable tool for investigating the biological roles of eicosatrienoic acid metabolites and for the development of novel pharmacological agents. This high-purity compound is essential for researchers and developers in the pharmaceutical, biotechnology, and advanced chemical synthesis sectors.

Application

• Biochemical Research: A critical reference standard and probe for studying the biosynthesis, metabolism, and biological activity of eicosatrienoic acid (EET) derivatives and related lipid mediators.
• Pharmaceutical Development: Serves as a key synthetic intermediate or a pharmacophore model in the discovery and development of novel anti-inflammatory, cardiovascular, or metabolic disease therapeutics.
• Enzyme Inhibition Studies: Used to investigate the function and inhibition of cytochrome P450 epoxygenases, soluble epoxide hydrolase (sEH), and other enzymes involved in the arachidonic acid cascade.
• Cell Signaling Pathway Analysis: Employed in cell-based assays to elucidate the role of specific eicosanoid metabolites in cellular communication, inflammation, and vascular function.
• Organic Synthesis: A versatile building block for the synthesis of more complex, labeled (e.g., deuterated, radiolabeled), or structurally modified eicosanoid analogs for advanced research.
• Analytical Standard: Used as a high-purity calibrant in liquid chromatography-mass spectrometry (LC-MS) and other analytical methods for the quantification of eicosanoids in biological samples.

Basic Information

Item	Details
Product Name	14-Iodo-15-Hydroxyeicosatrienoic Acid, Omega Lactone
CAS No.	78000-89-2
Molecular Formula	C20H31IO3
Molecular Weight	446.37 g/mol
Synonyms	14-Iodo-15-HETE-lactone; 14-Iodo-15-hydroxy-5Z,8Z,11Z-eicosatrienoic acid, δ-lactone; 14-I-15-HETEL; 14-Iodo-15-HETEL; Iodo-HETEL; Eicosatrienoic acid, 14-iodo-15-hydroxy-, lactone; (5Z,8Z,11Z)-14-Iodo-15-hydroxyeicosa-5,8,11-trienoic acid lactone
EINECS	Contact for details

Quality Control

Our 14-Iodo-15-Hydroxyeicosatrienoic Acid, Omega Lactone is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation via spectroscopic methods, and impurity profiles. We adhere to cGMP principles for the production of advanced pharmaceutical intermediates and research biochemicals.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation. For long-term storage, desiccate to protect against moisture. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Melting Point	Contact for details
Specific Rotation	Contact for details
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.