Description

Carbonimidic Difluoride, (2-Fluorophenyl)- (9Ci) is a specialized fluorinated building block of significant interest in advanced organic synthesis. Its core value lies in its ability to introduce the difluoromethylene (CF2) group, a key motif for modulating the physicochemical and metabolic properties of target molecules. This compound is essential for research chemists and process development scientists working in pharmaceuticals and agrochemicals, where precise fluorine incorporation is critical for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for incorporating CF2 groups to enhance metabolic stability, lipophilicity, and bioavailability.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and pesticides, where fluorine atoms improve biological activity and environmental persistence.
• Material Science Research: Serves as a monomer or modifying agent in the development of specialty polymers and advanced materials with unique surface properties or chemical resistance.
• Fluorine Chemistry Research: A valuable reagent for academic and industrial laboratories exploring new methodologies for C-F and C-CF2 bond formation.
• Ligand and Catalyst Development: Employed in the preparation of fluorinated ligands for catalysis, which can influence reaction selectivity and efficiency in metal-mediated transformations.

Basic Information

Product Name	Carbonimidic Difluoride, (2-Fluorophenyl)- (9Ci)
CAS No.	77897-06-4
Molecular Formula	C7H4F3N
Molecular Weight	159.11 g/mol
Synonyms	(2-Fluorophenyl)carbimidic Difluoride; 2-Fluorobenzimidoyl Difluoride; (2-Fluorophenyl)imidoyl Difluoride; N-(Difluoromethylene)-2-fluoroaniline; 2-Fluoro-N-(difluoromethylene)aniline; 2-Fluorobenzonitrile Difluoride; 2-Fluorophenyl Isocyanide Difluoride
EINECS	Contact for details

Quality Control

Every batch of Carbonimidic Difluoride, (2-Fluorophenyl)- (9Ci) is produced and analyzed under strict quality management protocols to ensure consistency and reliability for your critical synthetic applications. Our products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation, to meet the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.