Description

3'-Bromo-3,5,5'-Triiodothyronine is a halogenated derivative of the thyroid hormone triiodothyronine (T3). This compound is of significant interest in biochemical and pharmaceutical research, particularly as a molecular probe and synthetic intermediate. It is primarily utilized by research institutions and pharmaceutical development laboratories for studying thyroid hormone action, receptor binding, and metabolic pathways.

Application

• Biochemical Research: Used as a high-affinity ligand and molecular probe for investigating thyroid hormone receptors (TRα and TRβ).
• Pharmaceutical Development: Serves as a key synthetic intermediate or reference standard in the development of novel thyroid hormone analogs and metabolic modulators.
• Metabolic Studies: Employed in in vitro and in vivo studies to elucidate the mechanisms of thyroid hormone function and energy metabolism.
• Diagnostic Agent Research: Investigated for potential use in the development of diagnostic imaging agents due to its halogenated structure.
• Academic Research: A critical tool in university and institutional labs for endocrinology and hormone signaling pathway research.

Basic Information

Product Name	3'-Bromo-3,5,5'-Triiodothyronine
CAS No.	77667-01-7
Molecular Formula	C15H11BrI3NO4
Molecular Weight	788.87 g/mol
Synonyms	3'-Bromo-T3; Bromotriiodothyronine; 3'-Bromo-3,3',5-triiodo-L-thyronine; L-3'-Bromo-3,5,5'-triiodothyronine; 3'-Br-T3; (2S)-2-Amino-3-[4-(4-bromo-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid; NSC 113927
EINECS	Contact for details

Quality Control

Our 3'-Bromo-3,5,5'-Triiodothyronine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.