Description

Antineoplaston A10 is a synthetic derivative of phenylacetylglutamine, representing a significant compound in the field of experimental oncology research. Its primary value lies in its role as a key investigational agent for studying novel mechanisms of action against neoplastic cells. This product is essential for pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on developing innovative cancer therapeutics. The material is supplied as a high-purity reference standard to support preclinical studies and analytical method development.

Application

• Pharmaceutical Research & Development: Serves as a critical reference standard and active pharmaceutical ingredient (API) in preclinical studies for novel anticancer agents.
• Mechanistic Studies: Used to investigate the biochemical pathways and cellular mechanisms involved in the activity of antineoplaston compounds.
• Analytical Method Development: Employed as a certified reference material (CRM) for calibrating HPLC, LC-MS, and other analytical instruments in quality control laboratories.
• Academic Research: Facilitates basic science research in oncology, biochemistry, and molecular biology within university and institutional settings.
• Biotechnology Applications: Used in the development and screening of targeted cancer therapies and combination treatment protocols.
• Formulation Studies: Supports the development of stable dosage forms, including injectables, for experimental clinical trials.

Basic Information

Product Name	Antineoplaston A10
CAS No.	77658-84-5
Molecular Formula	C13H16N2O5
Molecular Weight	280.28 g/mol
Synonyms	Phenylacetylglutamine Disodium Salt; NSC 648539; Atengenal; Sodium Phenylacetylglutaminate; 3-(2-Phenylacetamido)-2,6-dioxopiperidine-4-acetic Acid Disodium Salt; A10; Antineoplaston A10 Disodium; Burzynski's Antineoplaston A10
EINECS	Contact for details

Quality Control

Our Antineoplaston A10 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR), purity assessment by HPLC, and determination of residual solvents and heavy metals. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting compliance with our stringent internal specifications. We support research requiring traceability and reliability in reference materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.