Description

Testosterone-16,16,17-D3 is a stable isotope-labeled analog of the primary male sex hormone, testosterone, specifically deuterated at the 16,16, and 17 positions. This compound is an essential internal standard for the precise and accurate quantification of testosterone in complex biological matrices using advanced analytical techniques like LC-MS/MS and GC-MS. It is primarily utilized by research institutions, clinical laboratories, and pharmaceutical companies engaged in endocrinology research, anti-doping analysis, and the development of hormone-based therapeutics.

Application

• Internal Standard for Mass Spectrometry: Critical for quantitative bioanalysis in pharmacokinetic and pharmacodynamic studies.
• Endocrine and Metabolic Research: Used in studies investigating androgen biosynthesis, metabolism, and related disorders.
• Clinical Diagnostics: Enables accurate measurement of testosterone levels in serum, plasma, and urine for diagnostic purposes.
• Anti-Doping Analysis: A key reference material in sports drug testing to detect the abuse of endogenous anabolic androgenic steroids.
• Pharmaceutical Development: Supports drug metabolism and stability studies for testosterone-based formulations and novel androgen receptor modulators.
• Forensic Toxicology: Assists in the confirmatory analysis of testosterone in forensic casework.

Basic Information

Product Name	Testosterone-16,16,17-D3
CAS No.	77546-39-5
Molecular Formula	C19H25D3O2
Molecular Weight	291.45 g/mol
Synonyms	Testosterone-d3; [16,16,17-D3]-Testosterone; 17β-Hydroxyandrost-4-en-3-one-16,16,17-d3; Androst-4-en-17β-ol-3-one-16,16,17-d3; Deuterated Testosterone; Testosterone (16,16,17-D3); 4-Androsten-17β-ol-3-one-16,16,17-d3
EINECS	Contact for details

Quality Control

Our Testosterone-16,16,17-D3 is manufactured under strict quality control protocols to ensure high chemical purity and isotopic enrichment, critical for its role as a quantitative standard. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as chemical purity, isotopic purity, and solvent content. We adhere to relevant industry standards for reference materials to ensure reliability and traceability in analytical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the product label/COA. Keep the container sealed in a dry, well-ventilated place. For long-term storage, consider storing under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity	≥ 98.0 atom % D
Isotopic Enrichment	≥ 99.0% at specified positions
Chemical Purity	≥ 95.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.