Description

Norhyodeoxycholic Acid CAS NO 77518-23-1 is a high-purity bile acid derivative, serving as a critical intermediate and reference standard in advanced pharmaceutical research and development. Its value lies in its specific stereochemistry and purity, which are essential for studying metabolic pathways and developing novel therapeutic agents. This compound is primarily needed by research institutions, pharmaceutical companies, and fine chemical manufacturers focused on hepatology, gastroenterology, and metabolic disorder treatments.

Application

• Pharmaceutical Intermediate: Key starting material or building block in the synthesis of novel therapeutic bile acid analogs and prodrugs.
• Biochemical Research: Used as a reference standard and reagent in studies of bile acid metabolism, liver function, and cholestatic diseases.
• Metabolic Pathway Analysis: Employed in in vitro and in vivo models to investigate the enterohepatic circulation and the role of secondary bile acids.
• Analytical Standard: Serves as a high-purity calibrant for HPLC, LC-MS, and other analytical methods in quality control and bioanalytical laboratories.
• Cell Culture & Enzymology: Utilized in studies involving nuclear receptors (e.g., FXR, TGR5) and enzymes involved in bile acid conjugation and transport.

Basic Information

Product Name	Norhyodeoxycholic Acid
CAS No.	77518-23-1
Molecular Formula	C23H38O4
Molecular Weight	378.55 g/mol
Synonyms	3α,6α-Dihydroxy-25-nor-5β-cholan-24-oic Acid; 25-Norhyodeoxycholic Acid; Norhyocholic Acid; 25-Norhyocholic Acid; 3α,6α-Dihydroxy-25-norcholan-24-oic Acid
EINECS	Contact for details

Quality Control

Our Norhyodeoxycholic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry guidelines to support our customers' regulatory and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.