Description

(2-Chloro-Phenyl)-Methanesulfonyl Chloride CAS NO 77421-13-7 is a versatile and highly reactive organosulfur compound, serving as a critical building block in advanced organic synthesis. Its primary value lies in its dual functionality as both an electrophile and a sulfonylating agent, enabling the construction of complex molecular architectures. This intermediate is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drugs, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides with sulfonyl moiety activity.
• Material Science: Used in the production of specialty polymers, liquid crystals, and advanced organic electronic materials.
• Chemical Research: A valuable reagent for method development and exploring new reaction pathways in organic chemistry.
• Dye and Pigment Manufacturing: Intermediate for synthesizing sulfonated dyes and colorants.

Basic Information

Product Name	(2-Chloro-Phenyl)-Methanesulfonyl Chloride
CAS No.	77421-13-7
Molecular Formula	C7H6Cl2O2S
Molecular Weight	225.09 g/mol
Synonyms	2-Chlorophenylmethanesulfonyl chloride; (2-Chlorophenyl)methanesulfonyl chloride; 1-(Chloromethylsulfonyl)-2-chlorobenzene; o-Chlorobenzylsulfonyl chloride; 2-Chlorobenzylsulfonyl chloride; α-Chloro-o-toluenesulfonyl chloride; (2-Chlorophenyl)methylsulfonyl chloride
EINECS	Contact for details

Quality Control

Our (2-Chloro-Phenyl)-Methanesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for fine chemical intermediates. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and reactive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.