Description

Vasopressin, Des-Tyr(2-Methyl)-4-Val-D-8-Arg- is a synthetic peptide analog of the endogenous hormone vasopressin, specifically engineered with targeted modifications to its amino acid sequence. This compound is of significant interest in advanced pharmaceutical research and development, particularly for studying receptor binding affinity and metabolic stability. It serves as a critical intermediate or reference standard for researchers and manufacturers in the fields of endocrinology, neuropharmacology, and peptide-based therapeutic discovery.

Application

• Pharmaceutical Research & Development: As a key reference standard or intermediate in the synthesis of novel vasopressin receptor agonists or antagonists.
• Biochemical Assay Development: For use in competitive binding assays and functional studies to characterize vasopressin receptor subtypes (V1a, V1b, V2).
• Metabolic Pathway Studies: Investigating the stability, degradation pathways, and pharmacokinetic profiles of modified peptide hormones.
• Academic & Institutional Research: A vital tool for universities and research institutes studying the central and peripheral effects of vasopressin analogs.
• Preclinical Development: Evaluation of therapeutic potential for conditions related to fluid balance, blood pressure regulation, and social behavior.
• Quality Control Laboratories: Serves as an analytical standard for the identification and quantification of related peptide substances.

Basic Information

Item	Detail
Product Name	Vasopressin, Des-Tyr(2-Methyl)-4-Val-D-8-Arg-
CAS No.	77403-95-3
Molecular Formula	C45H68N14O11S2
Molecular Weight	1021.23 g/mol
Synonyms	Des-Tyr(2-Me)-4-Val-D-8-Arg-vasopressin; [1-Deamino,2-O-methyltyrosine,4-valine,8-D-arginine]vasopressin; dAVP analog; Modified vasopressin fragment; Vasopressin (1-9) analog; [Mpa1, Tyr(Me)2, Val4, D-Arg8]VP; AVP analog 77403-95-3
EINECS	Contact for details

Quality Control

Our Vasopressin, Des-Tyr(2-Methyl)-4-Val-D-8-Arg- is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or development protocols. Our quality commitment aligns with cGMP principles for active pharmaceutical ingredients (APIs) and advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to reach room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Acetate Content (HPLC)	≤ 15.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.