Description

N1-[4-Amino-6-[[3-[Bis(2-Hydroxyethyl)Amino]Propyl]Amino]-6-Oxohexyl]-13-[(4-Amino-4,6-Dideoxy-α-L-Talopyranosyl)Oxy]-19-Demethyl-12-Hydroxybleomycinamide is a structurally complex, semi-synthetic derivative of the bleomycin family of glycopeptide antibiotics. This compound is of significant interest for its potential in advanced pharmaceutical research and development, particularly in the field of oncology. It is primarily utilized by research institutions, pharmaceutical developers, and fine chemical manufacturers focused on creating novel therapeutic agents and studying DNA interaction mechanisms.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of next-generation anti-cancer agents and antibiotic derivatives.
• Biochemical Research: Used as a reference standard or active compound in studies investigating DNA cleavage, cell cycle inhibition, and mechanisms of action of bleomycin analogues.
• Preclinical Development: Employed in the formulation and testing of new drug candidates targeting specific tumors in laboratory settings.
• Academic Research: Utilized in university and institutional labs for fundamental research in medicinal chemistry and molecular biology.
• Fine Chemical Synthesis: Acts as a specialized intermediate for custom synthesis projects requiring high-purity, complex glycopeptide structures.

Basic Information

Product Name	N1-[4-Amino-6-[[3-[Bis(2-Hydroxyethyl)Amino]Propyl]Amino]-6-Oxohexyl]-13-[(4-Amino-4,6-Dideoxy-α-L-Talopyranosyl)Oxy]-19-Demethyl-12-Hydroxybleomycinamide
CAS No.	77368-69-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Bleomycinamide derivative; 19-Demethyl-12-hydroxybleomycinamide derivative; Talisomycin derivative; BLM derivative; Antibiotic derivative 77368-69-5; Glycopeptide antibiotic intermediate; Complex bleomycin analogue
EINECS	Contact for details

Quality Control

Our N1-[4-Amino-6-[[3-[Bis(2-Hydroxyethyl)Amino]Propyl]Amino]-6-Oxohexyl]-13-[(4-Amino-4,6-Dideoxy-α-L-Talopyranosyl)Oxy]-19-Demethyl-12-Hydroxybleomycinamide is produced and handled under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.