Description

Oxytocin, 1-(β-Mercapto-Beta, β-Cyclopentamethylenepropionic Acid)-Orn(8)- is a synthetic, cyclic analog of the neuropeptide hormone oxytocin, designed with a disulfide bridge replacement for enhanced stability. This high-purity peptide is critical for research and development in neuroendocrinology and pharmacology, offering a more robust tool for studying receptor binding and signal transduction pathways. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and advanced biotechnology companies focusing on central nervous system therapeutics and peptide-based drug discovery.

Application

• Pharmacological Research: Used as a stable reference standard and tool compound for investigating oxytocin receptor (OTR) function and modulation.
• Neuroendocrine Studies: Essential for in vitro and in vivo studies on social behavior, stress response, and maternal physiology due to its resistance to reduction.
• Drug Discovery & Development: Serves as a key intermediate or active pharmaceutical ingredient (API) in the development of novel therapeutics for psychiatric and neurological disorders.
• Biochemical Assay Development: Employed in the calibration and validation of high-throughput screening (HTS) assays and diagnostic kits targeting the oxytocin pathway.
• Academic & Clinical Research: Provides a reliable reagent for exploring the role of oxytocin in autism spectrum disorders, anxiety, depression, and bonding behaviors.
• Peptide Chemistry & Stability Studies: Used as a model compound for studying the effects of disulfide bond mimetics on peptide conformation and metabolic stability.

Basic Information

Product Name	Oxytocin, 1-(β-Mercapto-Beta, β-Cyclopentamethylenepropionic Acid)-Orn(8)-
CAS No.	77327-42-5
Molecular Formula	C46H68N12O12S2
Molecular Weight	1021.22 g/mol
Synonyms	1-(β-Mercapto-β,β-cyclopentamethylenepropionic acid)-8-ornithine-oxytocin; [Mpa1, Orn8]-Oxytocin; Carbetocin Impurity; Desamino-1-carba-2-O-methyltyrosine-8-ornithine-oxytocin; Oxytocin, 1-(3-mercaptopropanoic acid)-8-ornithine-; Stable Oxytocin Analog; Tocinoic Acid, 1-deamino-1-(3-mercapto-3-cyclopentamethylenepropanoic acid)-8-ornithine-
EINECS	Contact for details

Quality Control

Our Oxytocin, 1-(β-Mercapto-Beta, β-Cyclopentamethylenepropionic Acid)-Orn(8)- is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for research and pharmaceutical development. Certificates of Analysis (COA) detailing purity, related substances, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.