Description

15-Fluoro-15-Deoxyprostaglandin F2α is a fluorinated analog of prostaglandin F2α, a key bioactive lipid mediator. This specific chemical modification enhances its metabolic stability and receptor selectivity, making it a valuable tool for advanced pharmacological research and development. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and fine chemical manufacturers focused on prostaglandin-based therapeutics and signaling pathway studies.

Application

• Pharmaceutical Research & Development: As a stable analog for studying prostaglandin F2α receptor (FP receptor) interactions, signal transduction, and downstream biological effects.
• Biochemical Tool Compound: Used in in vitro and cell-based assays to investigate roles in inflammation, smooth muscle contraction, and reproductive physiology.
• Reference Standard: Serves as a high-purity analytical standard for method development and quality control in the synthesis of prostaglandin-related APIs (Active Pharmaceutical Ingredients).
• Medicinal Chemistry: A key intermediate or building block for the synthesis of novel fluorinated prostaglandin derivatives with potential therapeutic applications.
• Ophthalmology Research: Investigation of intraocular pressure regulation and potential pathways relevant to glaucoma, given the role of prostaglandin analogs as first-line treatments.

Basic Information

Product Name	15-Fluoro-15-Deoxyprostaglandin F2α
CAS No.	77220-88-3
Molecular Formula	C₂₀H₃₃FO₅
Molecular Weight	372.47 g/mol
Synonyms	15-Fluoro-15-deoxy-PGF2α; Fluprostenol Impurity; 9α,11α,15S-Trihydroxy-15-fluoro-5Z,13E-prostadienoic Acid; 15-Fluoro-15-deoxyprostaglandin F2 alpha; (5Z,9α,11α,13E,15S)-9,11,15-Trihydroxy-15-fluoroprosta-5,13-dien-1-oic Acid; PGF2α 15-Fluoro Analog; Prostaglandin F2α 15-Fluoro Derivative
EINECS	Contact for details

Quality Control

Our 15-Fluoro-15-Deoxyprostaglandin F2α is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. For short-term use, the material may be stored at 2-8°C. Allow the sealed vial to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.