Description

18,19,20-Trinor-17-Cyclohexyl-13,14-Dehydroprostaglandin F2Alpha Methyl Ester is a synthetic prostaglandin analog, a key intermediate in advanced pharmaceutical research and development. This compound is valued for its structural specificity, enabling the study and synthesis of novel therapeutic agents targeting various physiological pathways. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of ophthalmic solutions, cardiovascular drugs, and other specialized medicinal products.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of advanced prostaglandin-based active pharmaceutical ingredients (APIs).
• Ophthalmic Research: Used in the development of next-generation glaucoma treatments and other intraocular pressure-regulating medications.
• Cardiovascular Drug Development: Serves as a precursor in research for drugs affecting vascular tone and platelet aggregation.
• Biochemical Research: Employed as a standard or probe in studies of prostaglandin receptors and signal transduction mechanisms.
• Process Chemistry: Utilized in scale-up and optimization studies for the commercial manufacturing of prostaglandin derivatives.

Basic Information

Product Name	18,19,20-Trinor-17-Cyclohexyl-13,14-Dehydroprostaglandin F2Alpha Methyl Ester
CAS No.	77204-95-6
Molecular Formula	C24H38O5
Molecular Weight	406.56 g/mol
Synonyms	17-Cyclohexyl-18,19,20-trinor-13,14-didehydro-PGF2α methyl ester; Methyl 17-cyclohexyl-18,19,20-trinor-13,14-didehydroprostaglandin F2α; 17-Cyclohexyl-13,14-didehydro-18,19,20-trinor-PGF2α methyl ester; Prostaglandin F2α analog methyl ester; PGF2α derivative; Cyclohexyl prostaglandin intermediate; Trinor prostaglandin methyl ester
EINECS	Contact for details

Quality Control

Our 18,19,20-Trinor-17-Cyclohexyl-13,14-Dehydroprostaglandin F2Alpha Methyl Ester is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled temperature of 2-8°C to minimize oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area, away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.