Description

Dezocine Glucuronide CAS NO 76948-31-7 is a key glucuronide metabolite of the synthetic opioid analgesic, Dezocine. This compound is of significant importance in pharmaceutical research and development, particularly in the fields of drug metabolism and pharmacokinetics (DMPK) studies. It serves as a critical reference standard for analytical method development, bioanalytical testing, and regulatory compliance. Professionals in pharmaceutical R&D, contract research organizations (CROs), and analytical laboratories require this high-purity metabolite to ensure accurate quantification and understanding of Dezocine's metabolic pathway.

Application

• Pharmaceutical Reference Standard: Primary use as a certified reference material (CRM) for quantitative analysis in bioequivalence and pharmacokinetic studies.
• Metabolite Identification & Profiling: Essential for in vitro and in vivo DMPK studies to map the metabolic fate of Dezocine.
• Bioanalytical Method Development: Used to develop and validate sensitive LC-MS/MS or HPLC-UV methods for plasma, serum, or urine analysis.
• Toxicology and Safety Assessment: Employed in studies to understand the safety profile and potential interactions of Dezocine metabolites.
• Impurity Characterization: Acts as a known impurity standard for the quality control of Dezocine active pharmaceutical ingredient (API) batches.
• Clinical Research: Supports clinical trials by enabling precise monitoring of metabolite levels in patient samples.

Basic Information

Product Name	Dezocine Glucuronide
CAS No.	76948-31-7
Molecular Formula	C24H35NO8
Molecular Weight	465.54 g/mol
Synonyms	Dezocine D6 Glucuronide; Dezocine Glucuronide Metabolite; (1R,5R,9R)-5,9-Dimethyl-2'-(-hydroxy-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-2'-hydroxy-6,7-benzomorphan-3-yl)methanone; Dezocine β-D-Glucuronide; Dezocine O-Glucuronide; Dezocine metabolite M1 (glucuronide); BW A575C Glucuronide
EINECS	Contact for details

Quality Control

Our Dezocine Glucuronide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS), to ensure it meets the high standards required for pharmaceutical reference materials. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment. We support compliance with GMP, ICH Q7, and relevant pharmacopeial guidelines for APIs and reference standards.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants and inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.