Description

15-Hydroxy-11 Alpha,9 α-(Epoxymethano)Prosta-5,13-Dienoic Acid is a high-purity prostaglandin derivative and a key synthetic intermediate in advanced pharmaceutical research and development. This compound is valued for its precise stereochemistry and structural complexity, which are critical for synthesizing bioactive molecules targeting specific physiological pathways. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, particularly in the fields of cardiovascular medicine, ophthalmology, and reproductive health.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of advanced prostaglandin analogs and related therapeutic agents.
• Biomedical Research: Used in biochemical and pharmacological studies to investigate prostaglandin receptor interactions and signal transduction mechanisms.
• Drug Discovery: Serves as a key precursor in medicinal chemistry programs aimed at developing new drugs for glaucoma, pulmonary hypertension, and other conditions.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling of prostaglandin-based pharmaceuticals.
• Chemical Synthesis: Utilized in organic synthesis for constructing complex, biologically active molecules with specific stereochemical configurations.

Basic Information

Product Name	15-Hydroxy-11 Alpha,9 α-(Epoxymethano)Prosta-5,13-Dienoic Acid
CAS No.	76898-47-0
Molecular Formula	C₂₁H₃₂O₅
Molecular Weight	364.48 g/mol
Synonyms	11α,15-Dihydroxy-9α,11α-epoxymethano-prosta-5,13-dien-1-oic acid; 15(S)-Hydroxy-11α,9α-(epoxymethano)prosta-5Z,13E-dien-1-oic acid; U-46619; 9,11-Epoxy-15-hydroxymethano-prosta-5,13-dienoic acid; 11-Deoxy-9,11-epoxymethano PGH₂; STA₂; Prostaglandin H2 analog; U46619
EINECS	Contact for details

Quality Control

Our 15-Hydroxy-11 Alpha,9 α-(Epoxymethano)Prosta-5,13-Dienoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) documenting purity, related substances, and other critical parameters are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or COA. Keep the container in a dry, well-ventilated area. For long-term storage, consider storing under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.