Description

Triacsin D is a potent and selective inhibitor of long-chain acyl-CoA synthetase (ACSL), a key enzyme in lipid metabolism. This compound is a critical research tool for studying fatty acid metabolism, lipid droplet formation, and related metabolic disorders. It is primarily utilized by researchers and scientists in the fields of biochemistry, metabolic disease research, and pharmaceutical development.

Application

• Biochemical Research: A selective tool for inhibiting ACSL isoforms to study fatty acid uptake, activation, and trafficking.
• Metabolic Disease Studies: Investigation of the role of lipid metabolism in conditions such as obesity, diabetes, and non-alcoholic fatty liver disease (NAFLD).
• Cell Biology: Used to modulate lipid droplet formation and dynamics in various cell culture models.
• Pharmaceutical Screening: Serves as a reference compound in drug discovery programs targeting metabolic enzymes.
• Academic Research: Fundamental research on lipid signaling pathways and energy homeostasis.

Basic Information

Product Name	Triacsin D
CAS No.	76896-81-6
Molecular Formula	C₂₀H₂₉N₃O₂
Molecular Weight	343.47 g/mol
Synonyms	Triacsin D; 1-Hydroxy-3-(E,E,E-2',4',7'-undecatrienylidine)triazene; ACSL Inhibitor III; Long-chain acyl-CoA synthetase inhibitor; (2E,4E,7E)-11-[3-Hydroxy-3-(1H-1,2,4-triazol-1-yl)propylidene]-2,4,7-undecatrienenitrile
EINECS	Contact for details

Quality Control

Our Triacsin D is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant quality standards for research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.