Description

2-(4-Chlorophenyl)Ethanesulfonyl Chloride is a versatile and reactive organosulfur compound primarily used as a key synthetic intermediate. Its value lies in its dual functionality, featuring both a sulfonyl chloride group and a chlorinated aromatic ring, enabling its use in the construction of more complex sulfonamide and sulfonate derivatives. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a critical building block for active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of sulfonamide-based drug candidates, including potential enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the production of novel herbicides, fungicides, and pesticides, leveraging the bioactive sulfonamide moiety.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Chemical Biology & Proteomics: Employed as a reactive handle for bioconjugation and the development of chemical probes targeting cysteine residues.
• Dye and Pigment Manufacturing: Acts as an intermediate in the synthesis of sulfonated dyes and colorants.
• Custom Synthesis and Contract Manufacturing: Supplied to fine chemical companies for bespoke synthesis projects and scale-up development.

Basic Information

Product Name	2-(4-Chlorophenyl)Ethanesulfonyl Chloride
CAS No.	76653-13-9
Molecular Formula	C8H8Cl2O2S
Molecular Weight	239.12 g/mol
Synonyms	4-Chlorophenylethanesulfonyl Chloride; 2-(4-Chlorophenyl)ethanesulfonyl chloride; 1-Chloro-2-(4-chlorophenyl)ethanesulfonyl chloride; p-Chlorophenethylsulfonyl Chloride; 4-Chlorobenzeneethanesulfonyl Chloride; (4-Chlorophenyl)ethanesulfonyl chloride; 76653-13-9
EINECS	Contact for details

Quality Control

Our 2-(4-Chlorophenyl)Ethanesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.