Description

Chonglou Saponin Ii CAS NO 76296-72-5 is a high-purity, bioactive saponin compound derived from the *Paris polyphylla* plant. This specialized phytochemical is valued for its significant pharmacological properties, making it a critical intermediate and reference standard for advanced research and development. It is primarily sought by the pharmaceutical, nutraceutical, and academic research sectors for applications in drug discovery, traditional medicine modernization, and biochemical studies.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quality control and standardization of herbal extracts and finished pharmaceutical products.
• Drug Discovery & Development: Serves as a key active pharmaceutical ingredient (API) intermediate in preclinical research for its anti-inflammatory, antitumor, and hemostatic properties.
• Nutraceutical Formulations: Incorporated into high-end dietary supplements and functional foods targeting immune support and wellness.
• Academic & Clinical Research: Essential for in-vitro and in-vivo studies investigating the mechanisms of saponins, pharmacokinetics, and new therapeutic pathways.
• Traditional Chinese Medicine (TCM): Used in the modernization and standardization of TCM formulas that utilize Chonglou (*Paris polyphylla*) for its purported medicinal benefits.
• Cosmeceutical Ingredients: Explored in premium skincare products for potential anti-aging and soothing effects due to its bioactive profile.

Basic Information

Product Name	Chonglou Saponin Ii
CAS No.	76296-72-5
Molecular Formula	C51H82O21
Molecular Weight	1031.18 g/mol
Synonyms	Polyphyllin II; Paris Saponin II; Chonglou Saponin II; Pennogenin 3-O-α-L-rhamnopyranosyl-(1→2)-[α-L-arabinofuranosyl-(1→4)]-β-D-glucopyranoside; Diosgenin 3-O-α-L-rhamnopyranosyl-(1→2)-[α-L-arabinofuranosyl-(1→4)]-β-D-glucopyranoside; Chonglou Saponin A; Saponin PE
EINECS	Contact for details

Quality Control

Our Chonglou Saponin Ii is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, to ensure it meets the stringent requirements for research and pharmaceutical use. A Certificate of Analysis (COA) detailing identity, purity, and impurities is provided with every shipment. We can supply material compliant with in-house pharmacopeial standards for use as a reference standard.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is sealed tightly after each use to minimize exposure to air and humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Loss on Drying	≤5.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm
Solubility	Soluble in methanol, DMSO; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.