Description

5-Bromo-2-Hydroxy-3-(Trifluoromethyl)Pyridine is a versatile halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring bromine and trifluoromethyl substituents, makes it a high-value intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a molecular scaffold or tagging reagent in the design of enzyme inhibitors, probes, and other biochemical tools.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	5-Bromo-2-Hydroxy-3-(Trifluoromethyl)Pyridine
CAS No.	76041-79-7
Molecular Formula	C6H3BrF3NO
Molecular Weight	241.99 g/mol
Synonyms	5-Bromo-3-(trifluoromethyl)pyridin-2-ol; 2-Hydroxy-5-bromo-3-trifluoromethylpyridine; 5-Bromo-2-hydroxy-3-trifluoromethylpyridine; 3-Trifluoromethyl-5-bromopyridin-2-ol; 5-Bromo-3-trifluoromethyl-2-pyridinol; 2-Pyridinol, 5-bromo-3-(trifluoromethyl)-; 5-Bromo-3-(trifluoromethyl)-2-pyridone (tautomer)
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Hydroxy-3-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.