Description

19-Noraldosterone is a significant synthetic steroid derivative, structurally related to the mineralocorticoid hormone aldosterone. This compound is primarily utilized as a key reference standard and a critical intermediate in advanced pharmaceutical research and development. It is essential for scientists and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who are engaged in metabolic studies, analytical method development, and the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis (e.g., HPLC, LC-MS) of aldosterone pathway compounds in research and quality control laboratories.
• Biochemical Research: Serves as a crucial tool in studying mineralocorticoid receptor (MR) activity, hormone metabolism, and related endocrine pathways.
• Active Pharmaceutical Ingredient (API) Intermediate: Acts as a high-purity building block in the multi-step synthesis of potential steroid-based therapeutics.
• Metabolite Studies: Employed in the investigation of steroid hormone biotransformation and the identification of novel metabolites in preclinical and clinical studies.
• Diagnostic Kit Development: Used in the development and calibration of immunoassays and other diagnostic tests targeting the renin-angiotensin-aldosterone system (RAAS).

Basic Information

Item	Detail
Product Name	19-Noraldosterone
CAS No.	76025-75-7
Molecular Formula	C21H28O5
Molecular Weight	360.45 g/mol
Synonyms	19-Noraldosterone; 11β,21-Dihydroxy-3,20-dioxo-19-norpregn-4-en-18-al; 18-Aldo-19-norprogesterone; 19-Nor-aldosterone; 19-Nor Aldosterone; Aldosterone 19-nor derivative
EINECS	Contact for details

Quality Control

Every batch of our 19-Noraldosterone is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and support our products with a detailed Certificate of Analysis (COA), which includes data from HPLC, NMR, and mass spectrometry. Our quality commitment aligns with the standards expected for pharmaceutical intermediates and reference materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.