Description

16,16-Dimethyl-6-Keto Prostaglandin E1 is a synthetic analog of prostaglandin E1, specifically engineered for enhanced metabolic stability and targeted biological activity. This compound is a critical advanced intermediate in pharmaceutical research and development, particularly for investigating vascular and inflammatory pathways. It is primarily utilized by researchers and manufacturers in the life sciences sector for developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates targeting cardiovascular and inflammatory diseases.
• Biochemical Research: Used as a reference standard and probe in studies of prostaglandin receptors (EP receptors) and their signaling mechanisms.
• Vasodilation Studies: Employed in preclinical research to investigate compounds that promote blood vessel dilation and improve circulation.
• Anti-inflammatory Agent Development: Acts as a precursor or model compound for creating new anti-inflammatory medications with improved stability profiles.
• Cell Culture & Cytoprotection: Applied in cell-based assays to study cytoprotective effects and cellular response modulation.

Basic Information

Product Name	16,16-Dimethyl-6-Keto Prostaglandin E1
CAS No.	75874-32-7
Molecular Formula	C22H36O6
Molecular Weight	396.52 g/mol
Synonyms	16,16-Dimethyl-PGE1; 6-Keto-16,16-dimethylprostaglandin E1; 11α,15α-Dihydroxy-16,16-dimethyl-9-oxoprosta-5,13-dien-1-oic acid; 16,16-Dimethyl-6-oxo-PGE1; 6-Keto-16,16-dimethyl PGE1; DM-6-keto-PGE1; 16,16-Dimethyl-6-keto Prostaglandin E1
EINECS	Contact for details

Quality Control

Our 16,16-Dimethyl-6-Keto Prostaglandin E1 is manufactured under strict quality systems suitable for research and development applications. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure consistency and reliability. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.