Description

3,5,6-Trifluoro-2-Hydroxypyridine is a fluorinated pyridine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique electronic properties imparted by the trifluoro and hydroxyl substituents, which make it an essential intermediate for creating complex molecules. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms enhance biological activity and stability.
• Material Science Research: Serves as a precursor for specialty chemicals and functional materials, including ligands for catalysis.
• Organic Synthesis Building Block: Employed in cross-coupling reactions and other transformations to introduce the trifluorohydroxypyridine moiety into target molecules.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry in both academic and industrial R&D settings.

Basic Information

Product Name	3,5,6-Trifluoro-2-Hydroxypyridine
CAS No.	75777-49-0
Molecular Formula	C5H2F3NO
Molecular Weight	149.07 g/mol
Synonyms	2-Hydroxy-3,5,6-trifluoropyridine; 3,5,6-Trifluoro-2-pyridinol; 2-Pyridinol, 3,5,6-trifluoro-; 3,5,6-Trifluoro-2(1H)-pyridinone; 3,5,6-Trifluoropyridin-2-ol; 3,5,6-Trifluoro-2-hydroxypyridine; 3,5,6-Trifluoro-2-oxo-1,2-dihydropyridine
EINECS	Contact for details

Quality Control

Our 3,5,6-Trifluoro-2-Hydroxypyridine is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Recommended storage temperature is 2-8°C for long-term stability. The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.