Description

Hexadecanoic-16,16,16-D3 Acid is a stable isotope-labeled analog of palmitic acid, where three deuterium atoms replace the terminal methyl hydrogens. This high-purity labeled compound is essential for applications requiring precise internal standards in quantitative mass spectrometry and metabolic research. It is primarily utilized by analytical laboratories, pharmaceutical R&D departments, and academic institutions conducting lipidomics, tracer studies, and drug metabolism investigations.

Application

• Internal Standard for Quantitative Analysis: Serves as a critical deuterated internal standard in GC-MS and LC-MS for the accurate quantification of natural palmitic acid and related lipids in complex biological matrices.
• Metabolic Tracer Studies: Used in stable isotope labeling experiments to trace fatty acid metabolism, β-oxidation pathways, and lipid biosynthesis in cell cultures, tissues, or whole organisms.
• Pharmaceutical Research: Enables precise pharmacokinetic and bioavailability studies of lipid-based drug formulations through isotope dilution mass spectrometry techniques.
• Clinical Diagnostics: Supports the development and validation of advanced diagnostic assays for metabolic disorders by providing a reliable reference compound.
• Nutritional Science: Facilitates research into dietary fat absorption, storage, and mobilization in nutritional and obesity studies.
• Biomarker Discovery: Aids in the identification and validation of lipid biomarkers for various disease states by improving analytical precision.

Basic Information

Product Name	Hexadecanoic-16,16,16-D3 Acid
CAS No.	75736-53-7
Molecular Formula	C16H29D3O2
Molecular Weight	259.43 g/mol
Synonyms	Palmitic Acid-d3; Hexadecanoic-d3 Acid; [16,16,16-D3]Palmitic Acid; n-Hexadecanoic-16,16,16-d3 Acid; Deuterated Palmitic Acid; Palmitic Acid (D3, 16,16,16); C16:0-d3; Isotopic Labeled Palmitate
EINECS	Contact for details

Quality Control

Our isotope-labeled chemicals are produced and tested under stringent quality management systems to ensure exceptional isotopic purity and chemical integrity. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as chemical purity (by GC or HPLC), isotopic enrichment (by MS), and solvent content. We adhere to relevant industry standards for high-purity reference materials. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). For long-term storage under an inert atmosphere such as argon or nitrogen is recommended to maintain optimal stability and isotopic purity.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Assay (HPLC/GC)	≥ 98.0% (Chemical Purity)
Isotopic Enrichment	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.