Description

Calcitonin, Salmon, Des-Ser(2)- is a synthetic analog of the natural polypeptide hormone, specifically engineered for enhanced stability and biological activity. This high-purity peptide is critical for research and development in metabolic bone disorders and calcium homeostasis studies. It is an essential raw material for pharmaceutical manufacturers, academic research institutions, and biotechnology companies focused on endocrinology and osteoporosis therapeutics. The compound is supplied under stringent quality control to ensure batch-to-batch consistency for reliable experimental and formulation outcomes.

Application

• Pharmaceutical Active Ingredient: Primary use as the active pharmaceutical ingredient (API) in injectable formulations for the treatment of Paget's disease, hypercalcemia, and postmenopausal osteoporosis.
• Biomedical Research: Critical tool for in vitro and in vivo studies investigating bone metabolism, osteoclast activity, and calcium/phosphate regulation.
• Reference Standard: Serves as a high-purity chemical reference standard (CRS) for analytical method development, validation, and quality control testing in pharmaceutical laboratories.
• Peptide Chemistry Studies: Used as a model compound in research focusing on peptide stability, structure-activity relationships (SAR), and analog development.
• Diagnostic Development: Potential use in the development of immunoassays and diagnostic kits for measuring calcitonin levels in clinical settings.

Basic Information

Product Name	Calcitonin, Salmon, Des-Ser(2)-
CAS No.	75660-90-1
Molecular Formula	C₁₄₅H₂₄₀N₄₄O₄₈S₂
Molecular Weight	~3431.9 g/mol
Synonyms	Des-Ser(2)-Calcitonin (Salmon); Salmon Calcitonin (1-32), Des-Serine-2; [Des-Ser²]-sCT; Calcitonin Salmon, Des-Serine-2; SCT(1-32), Des-Ser²; Calcitonin (salmon) fragment 1-32, 2-L-serine; UNII-1J24QQD49M; Salcatonin, Des-Ser(2)-
EINECS	Contact for details

Quality Control

Our Calcitonin, Salmon, Des-Ser(2)- is manufactured and tested to meet exacting standards for pharmaceutical research and development. Each batch is subjected to a comprehensive battery of analytical tests, including HPLC for purity, peptide mapping for sequence confirmation, and tests for related substances and residual solvents. We provide full traceability and support regulatory filings. Certificates of Analysis (COA) detailing all test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at a controlled room temperature of 15-25°C or as specified on the label. This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccated conditions at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Water Content (KF)	≤ 5.0%
Peptide Content (UV)	≥ 80.0%
Bacterial Endotoxins	< 5.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.