Description

(1,1,2-Trifluoroethyl)-Benzene is a specialized fluorinated aromatic compound, also known as 1,1,2-Trifluoroethylbenzene. This chemical is valued for its unique combination of a benzene ring and a trifluoroethyl group, making it a versatile intermediate for introducing fluorine into complex molecular architectures. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and advanced materials sectors for applications requiring precise fluorination.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs to enhance metabolic stability, bioavailability, and membrane permeability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the trifluoroethyl group can improve efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor in the production of fluorinated components for electronic displays and organic light-emitting diodes (OLEDs), contributing to improved performance and durability.
• Specialty Polymer Modifier: Incorporated to impart specific properties like chemical resistance, thermal stability, or altered surface characteristics to high-performance polymers and coatings.
• Organic Synthesis Reagent: Employed in research laboratories for novel organic transformations, including cross-coupling reactions and as a source of the -CH2CF3 moiety.

Basic Information

Product Name	(1,1,2-Trifluoroethyl)-Benzene
CAS No.	75600-46-3
Molecular Formula	C8H7F3
Molecular Weight	160.14 g/mol
Synonyms	1,1,2-Trifluoroethylbenzene; (2,2,2-Trifluoroethyl)benzene; α,α,β-Trifluoroethylbenzene; Benzyltrifluoride; Phenyl(trifluoroethyl); EINECS 278-196-8; (Trifluoroethyl)benzene
EINECS	278-196-8

Quality Control

Every batch of (1,1,2-Trifluoroethyl)-Benzene is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming specifications for identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong bases. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration changes. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances (GC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.