Description

Glycolic-2,2-D2 Acid CAS NO 75502-10-2 is a deuterium-labeled isotopologue of glycolic acid, where two hydrogen atoms at the 2-position are replaced with deuterium. This stable isotope-labeled compound is essential for advanced research and analytical applications where precise molecular tracking and differentiation are required. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry sectors for use as an internal standard in mass spectrometry, metabolic pathway studies, and the synthesis of labeled complex molecules.

Application

• Internal Standard for Quantitative Analysis: Serves as a critical deuterated internal standard in LC-MS and GC-MS for the accurate quantification of glycolic acid and related metabolites in complex biological and environmental matrices.
• Metabolic Research & Tracer Studies: Used in isotopic labeling experiments to investigate metabolic pathways, enzyme mechanisms, and pharmacokinetics in biomedical and plant science research.
• Synthesis of Deuterated Compounds: Acts as a key building block for the synthesis of more complex deuterium-labeled fine chemicals, pharmaceuticals, and agrochemicals, enabling studies on isotope effects.
• NMR Spectroscopy: Provides a valuable tool in Nuclear Magnetic Resonance (NMR) spectroscopy for spectral referencing and method development due to its distinct isotopic signature.
• Pharmaceutical Development: Employed in drug discovery and development for tracing the fate of active pharmaceutical ingredients and their metabolites.

Basic Information

Product Name	Glycolic-2,2-D2 Acid
CAS No.	75502-10-2
Molecular Formula	C₂H₂D₂O₃
Molecular Weight	78.07 g/mol
Synonyms	2,2-Dideuteroglycolic Acid; [2,2-D₂]Glycolic Acid; Hydroxyacetic-2,2-d2 Acid; Deuterated Glycolic Acid; Glycolic Acid-d2; (2,2-Dideutero-2-hydroxyacetic) Acid; Hydroxy(dideutero)acetic Acid; α-Hydroxy-d2-acetic Acid
EINECS	Contact for details

Quality Control

Our deuterium-labeled Glycolic Acid is produced and handled under controlled conditions to ensure isotopic and chemical purity. Each batch undergoes rigorous analytical testing, including NMR and mass spectrometry, to confirm isotopic enrichment and chemical identity. Certificates of Analysis (COA) detailing batch-specific results for assay, isotopic purity, and chemical purity are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Isotopic Purity (D₂)	≥ 98 atom % D
Assay (HPLC)	≥ 97% (chemical purity)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.