Description

1-Chloromethyl-4-(1,2,2,2-Tetrafluoro-1-Trifluoromethyl-Ethyl)-Benzene is a high-value, multi-fluorinated aromatic building block essential for advanced chemical synthesis. This compound matters because its unique structure, featuring both a reactive chloromethyl group and a highly fluorinated side chain, enables the precise introduction of lipophilic and electron-withdrawing properties into target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring enhanced lipophilicity and metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the fluorine motifs improve biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor for fluorinated components in liquid crystal displays (LCDs), contributing to improved dielectric anisotropy and stability.
• Advanced Polymer Modifier: Incorporated into specialty polymers to impart unique surface properties, chemical resistance, and low refractive index.
• Organic Electronics: Acts as a starting material for synthesizing charge-transport or emissive layers in organic light-emitting diodes (OLEDs) and other electronic devices.
• Fluorinated Surfactant Precursor: Used to develop high-performance surfactants and surface modifiers with exceptional oil and water repellency.

Basic Information

Product Name	1-Chloromethyl-4-(1,2,2,2-Tetrafluoro-1-Trifluoromethyl-Ethyl)-Benzene
CAS No.	75462-58-7
Molecular Formula	C10H5ClF7
Molecular Weight	296.59 g/mol
Synonyms	α,α,α,ω-Tetrahydro-4-(chloromethyl)benzotrifluoride (Heptafluoro Derivative); 4-(Chloromethyl)-α,α,α,ω-tetrahydrobenzotrifluoride; 1-(Chloromethyl)-4-(1,2,2,2-tetrafluoro-1-trifluoromethylethyl)benzene; p-(Chloromethyl)benzyl Heptafluoroisopropyl Ether (incorrect but common); Benzene, 1-chloromethyl-4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-; C10H5ClF7; Heptafluoroisopropyl Benzyl Chloride Analog
EINECS	Contact for details

Quality Control

Our 1-Chloromethyl-4-(1,2,2,2-Tetrafluoro-1-Trifluoromethyl-Ethyl)-Benzene is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. We employ advanced analytical techniques including GC, HPLC, and NMR to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is compatible with strong acids and organic solvents but should be kept away from strong bases and oxidizing agents. Keep the container tightly sealed when not in use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Purity (HPLC)	≥ 96.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.