Description

Saxitoxinol is a potent marine neurotoxin analog, a key derivative in the saxitoxin family. This compound is of critical importance for advanced scientific research, particularly in the study of voltage-gated sodium channel blockers and their mechanisms of action. It serves as an essential reference standard and research chemical for toxicologists, pharmacologists, and analytical laboratories focused on marine biotoxins and neuropharmacology.

Application

• Neuroscience Research: Primary tool for studying the binding and inhibitory effects on neuronal sodium channels.
• Toxicology & Pharmacology: Used as a reference standard in the investigation of paralytic shellfish poisoning (PSP) toxins and their metabolic pathways.
• Analytical Method Development: Critical for calibrating and validating advanced analytical techniques such as LC-MS/MS for the detection of saxitoxin analogs in environmental and biological samples.
• Biomedical Research: Employed in studies exploring potential therapeutic applications of sodium channel modulators for pain management and neurological disorders.
• Environmental Monitoring: Serves as a calibration standard in monitoring programs for harmful algal blooms (HABs) and seafood safety.
• Pharmaceutical Development: Used in early-stage research for drug discovery programs targeting ion channels.

Basic Information

Product Name	Saxitoxinol
CAS No.	75420-34-7
Molecular Formula	C10H17N7O4
Molecular Weight	299.29 g/mol
Synonyms	STX-ol; Saxitoxinol dihydrochloride; (3aS,4R,9aS)-2,6-Diamino-4-(((aminocarbonyl)oxy)methyl)-3a,4,8,9-tetrahydro-1H,7H-pyrrolo[1,2-c]purine-7,9-dione; 11-Hydroxysaxitoxin; PSP Toxin C2; GTX-8; Paralytic Shellfish Poison C2
EINECS	Contact for details

Quality Control

Our Saxitoxinol is produced and handled under strict quality protocols suitable for research applications. Each batch undergoes rigorous analytical testing, including HPLC and LC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay results, and analytical methods is provided with every shipment to support your research integrity and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment. For long-term stability, consider storage at -20°C under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.