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13,14-Dihydro-15-Keto Prostaglandin A2 CAS NO 74872-89-2


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CAS No.:74872-89-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

13,14-Dihydro-15-Keto Prostaglandin A2 is a specialized prostaglandin analog and a key metabolite in the arachidonic acid cascade. This compound is of significant interest for its role as a biochemical tool in research and as a potential synthetic intermediate. It is primarily utilized by pharmaceutical R&D laboratories and academic institutions focused on prostaglandin biology, inflammation studies, and metabolic pathway analysis.

Application

  • Biochemical Research: Used as a reference standard and analytical tool in the study of prostaglandin metabolism and signaling pathways.
  • Pharmaceutical Development: Serves as a critical intermediate or precursor in the synthesis of novel therapeutic agents targeting inflammation and related disorders.
  • Cell Biology Studies: Employed in in vitro assays to investigate cellular responses, receptor interactions, and the effects of prostaglandin derivatives.
  • Analytical Chemistry: Used as a high-purity standard for method development and validation in chromatographic analysis (HPLC, LC-MS).
  • Metabolite Analysis: Essential for the identification and quantification of prostaglandin metabolites in biological samples.

Basic Information

Product Name 13,14-Dihydro-15-Keto Prostaglandin A2
CAS No. 74872-89-2
Molecular Formula C₂₀H₃₂O₅
Molecular Weight 352.47 g/mol
Synonyms 15-Keto-13,14-dihydro-PGA2; 15-Oxo-13,14-dihydroprostaglandin A2; DHK-PGA2; 13,14-Dihydro-15-oxoprostaglandin A2; PGA2 metabolite; (5Z)-7-[(1R,2R,3R)-3-Hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl]hept-5-enoic acid
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Quality Control

Our 13,14-Dihydro-15-Keto Prostaglandin A2 is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong acids and bases.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 1.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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