Description

5-(Trifluoromethyl)Pyridin-2-Amine is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced chemical synthesis. Its trifluoromethyl group and amine functionality make it a versatile intermediate for creating compounds with enhanced metabolic stability and lipophilicity. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group can improve biological activity and environmental stability.
• Material Science Precursor: Employed in the synthesis of specialized ligands, catalysts, and fluorinated polymers for high-performance materials.
• Chemical Research & Development: Serves as a fundamental building block in medicinal chemistry and organic synthesis for structure-activity relationship (SAR) studies.
• Liquid Crystal & Electronic Chemicals: Can be utilized in the synthesis of fluorinated components for electronic materials and display technologies.

Basic Information

Product Name	5-(Trifluoromethyl)Pyridin-2-Amine
CAS No.	74784-70-6
Molecular Formula	C6H5F3N2
Molecular Weight	162.11 g/mol
Synonyms	2-Amino-5-(trifluoromethyl)pyridine; 5-(Trifluoromethyl)-2-pyridinamine; 2-Pyridinamine, 5-(trifluoromethyl)-; α,α,α-Trifluoro-2-amino-5-picoline; 5-Trifluoromethylpyridin-2-ylamine; 5-Trifluoromethyl-2-aminopyridine; 2-Amino-α,α,α-trifluoro-5-picoline
EINECS	Contact for details

Quality Control

Our 5-(Trifluoromethyl)Pyridin-2-Amine is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistent performance. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.