Description

(8R)-8β-Hydroxyverrucarin A is a macrocyclic trichothecene derivative, a class of sesquiterpenoid mycotoxins known for their potent biological activity. This specific hydroxy derivative is of significant interest in advanced biochemical and pharmacological research due to its unique structural modifications. It serves as a critical reference standard and a valuable synthetic intermediate for researchers in the fields of toxicology, mycology, and medicinal chemistry.

Application

• Biochemical Research Standard: Used as a high-purity analytical reference standard for the identification and quantification of trichothecene mycotoxins in complex matrices.
• Pharmacological Studies: Employed in in vitro and in vivo research to investigate the structure-activity relationships, cytotoxicity, and potential mechanisms of action of trichothecene compounds.
• Mycotoxin Analysis: A key compound in the development and validation of analytical methods, such as HPLC-MS and ELISA, for food safety and environmental monitoring.
• Medicinal Chemistry: Acts as a sophisticated building block or a lead compound for the synthesis of novel analogs with targeted biological properties.
• Toxicology Research: Utilized in studies focused on understanding the toxicological pathways and cellular impacts of sesquiterpenoid mycotoxins.

Basic Information

Product Name	(8R)-8β-Hydroxyverrucarin A
CAS No.	74608-63-2
Molecular Formula	C₂₇H₃₄O₉
Molecular Weight	502.56 g/mol
Synonyms	8β-Hydroxyverrucarin A; (8R)-8-Hydroxyverrucarin A; Verrucarin A, 8β-hydroxy-; 8β-Hydroxy-verrucarin A; NSC 339593; 8-Hydroxyverrucarin A; 8beta-Hydroxyverrucarin A
EINECS	Contact for details

Quality Control

Every batch of (8R)-8β-Hydroxyverrucarin A is produced and analyzed under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing comprehensive analytical results, including HPLC purity, are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.