Description

(18R,19R)-Lup-12-En-3β-Ol CAS NO 74523-79-8 is a high-purity lupane-type triterpenoid compound, a specific stereoisomer of betulin. This compound matters as a critical reference standard and advanced intermediate for pharmaceutical research, particularly in the development of anti-inflammatory, antiviral, and anticancer agents. It is needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on natural product chemistry and drug discovery.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control of betulin-derived APIs and herbal extracts.
• Drug Discovery Intermediate: Serves as a key chiral building block for the semi-synthesis of novel therapeutic agents targeting various diseases.
• Natural Product Research: Employed in academic and industrial research to study structure-activity relationships (SAR) of triterpenoids and their biological mechanisms.
• Cosmetic & Skincare Actives: Investigated for potential use in high-end cosmetic formulations for its purported anti-aging and skin-soothing properties.
• Biochemical Tool Compound: Utilized in vitro and in vivo studies to probe specific biological pathways and enzyme interactions.

Basic Information

Product Name	(18R,19R)-Lup-12-En-3β-Ol
CAS No.	74523-79-8
Molecular Formula	C30H50O
Molecular Weight	426.73 g/mol
Synonyms	(3β)-Lup-12-en-3-ol, (18R,19R)-; (18R,19R)-Betulin; Lup-12-ene-3β-ol; Betulin (specific stereoisomer); 3β-Hydroxylup-12-en-28-oic acid (lupane skeleton); White Birch Triterpene; Betulinol; Trochol
EINECS	Contact for details

Quality Control

Our (18R,19R)-Lup-12-En-3β-Ol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, chiral analysis for stereochemical confirmation, and identity verification via NMR and MS. We provide Certificates of Analysis (COA) with detailed chromatographic data and can supply material suitable for use as a reference standard, supported by analytical documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. This compound is stable under these conditions but should be handled to minimize prolonged exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% (by Chiral HPLC)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.