Description

8-Ketoverrucarin A is a specialized macrocyclic trichothecene derivative, a class of compounds known for their potent biological activities. This high-purity reference standard is critical for pharmaceutical research and development, particularly in the study of mycotoxins and their biochemical pathways. It is primarily utilized by research institutions, pharmaceutical companies, and analytical laboratories engaged in toxicology, natural product chemistry, and drug discovery programs.

Application

• Pharmaceutical Reference Standard: Serves as a certified analytical standard for method development, validation, and quality control in drug discovery and safety testing.
• Biochemical Research: Used as a tool compound to investigate the mechanisms of action, toxicity, and cellular effects of trichothecene mycotoxins.
• Natural Product Isolation & Analysis: Acts as a key marker or comparator in the isolation, purification, and structural elucidation of related fungal metabolites.
• Toxicology Studies: Employed in in-vitro and in-vivo studies to assess the toxicological profile and environmental impact of trichothecene contaminants.
• Academic Research: Supports fundamental research in mycology, organic chemistry, and medicinal chemistry at universities and specialized institutes.

Basic Information

Product Name	8-Ketoverrucarin A
CAS No.	74516-63-5
Molecular Formula	C27H34O9
Molecular Weight	502.56 g/mol
Synonyms	8-Ketoverrucarin A; Verrucarin J; 12,13-Epoxytrichothec-9-ene-4,8,15-triol, 3-acetate 15-(3-methylbutanoate); NSC 339213; 8-Oxoverrucarin A; 8-Keto-verrucarin A; (3α,4β,8α)-4,15-Bis(acetyloxy)-3-(3-methyl-1-oxobutoxy)-12,13-epoxytrichothec-9-en-8-one
EINECS	Contact for details

Quality Control

Our 8-Ketoverrucarin A is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and integrity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and MS to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. For short-term use, the material may be stored at 2-8°C. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation. This product is intended for research use only in a laboratory setting.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.