Description

12-Deoxyphorbol-13-Phenylacetate-20-(4-Butoxyphenylacetate) is a high-purity, synthetic phorbol ester derivative of significant interest in advanced biochemical and pharmacological research. This compound serves as a critical reference standard and a potent, selective tool compound for studying protein kinase C (PKC) signaling pathways and related biological mechanisms. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in oncology, immunology, and cell signaling studies. The precise structure and activity of this molecule make it an invaluable asset for developing novel therapeutic strategies and diagnostic assays.

Application

• Biochemical Research: As a potent and specific activator of protein kinase C (PKC) isoforms for studying signal transduction, cell proliferation, and differentiation.
• Pharmaceutical R&D: Used as a reference standard and pharmacological tool in the discovery and validation of new drug targets, particularly in oncology and inflammatory diseases.
• Cell Biology Studies: Employed to investigate the role of PKC in cellular processes such as apoptosis, tumor promotion, and immune response modulation.
• Academic Research: A key reagent for universities and research institutes exploring the molecular mechanisms of phorbol esters and their interactions with biological systems.
• Assay Development: Utilized as a control compound in high-throughput screening (HTS) assays and in vitro diagnostic test development.

Basic Information

Product Name	12-Deoxyphorbol-13-Phenylacetate-20-(4-Butoxyphenylacetate)
CAS No.	74513-81-8
Molecular Formula	C46H52O8
Molecular Weight	732.9 g/mol
Synonyms	12-Deoxyphorbol 13-phenylacetate 20-(4-butoxyphenylacetate); 12-Deoxyphorbol-13-phenylacetate-20-(4-butoxyphenylacetate); 12-Deoxyphorbol 13-phenylacetate-20-(4-butoxyphenylacetate); 4-Butoxyphenylacetic Acid 12-Deoxyphorbol-13-phenylacetate; Prostratin analog; PKC activator derivative; Synthetic phorbol ester
EINECS	Contact for details

Quality Control

Our 12-Deoxyphorbol-13-Phenylacetate-20-(4-Butoxyphenylacetate) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications. We support research compliance with traceable documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing at -20°C under an inert atmosphere to ensure maximum stability. Keep the container tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.