Description

2-Chloro-3-Methylbenzotrifluoride is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its core value lies in the trifluoromethyl and chloro substituents, which are key motifs for modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. This compound is primarily needed by R&D and production chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A critical synthon for the preparation of bioactive molecules, including potential enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity.
• Material Science Research: Serves as a precursor for specialty monomers or ligands in the development of advanced polymers and functional materials.
• Liquid Crystal & OLED Materials: Employed in the synthesis of fluorinated components for electronic display and lighting applications.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions (e.g., Suzuki, Stille) for constructing complex biaryl systems.

Basic Information

Product Name	2-Chloro-3-Methylbenzotrifluoride
CAS No.	74483-48-0
Molecular Formula	C8H6ClF3
Molecular Weight	194.58 g/mol
Synonyms	1-Chloro-2-methyl-3-(trifluoromethyl)benzene; 2-Chloro-α,α,α-trifluoro-m-xylene; 3-Methyl-2-chlorobenzotrifluoride; 2-Chloro-3-(trifluoromethyl)toluene; m-Xylene, 2-chloro-α,α,α-trifluoro-; Benzene, 1-chloro-2-methyl-3-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Methylbenzotrifluoride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 2.0%
Density (20°C)	~1.35 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.