Description

11-Deoxy-11Alpha-(2-Hydroxyethylthio)-Prostaglandin E2 Methyl Ester is a chemically modified prostaglandin analog, a key synthetic intermediate in advanced pharmaceutical research and development. This compound is valued for its role in the synthesis of novel therapeutic agents targeting inflammatory pathways and ocular conditions. It is primarily utilized by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in prostaglandin-based drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel prostaglandin-based therapeutics.
• Ophthalmic Drug Research: Used in the development of next-generation treatments for glaucoma and ocular hypertension.
• Inflammatory Pathway Studies: Serves as a key reagent in biochemical research focused on prostaglandin receptors and signaling mechanisms.
• Process Chemistry & Scale-Up: Employed in the optimization and production of active pharmaceutical ingredients (APIs) for clinical trials.
• Reference Standard: Used as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	11-Deoxy-11Alpha-(2-Hydroxyethylthio)-Prostaglandin E2 Methyl Ester
CAS No.	74412-44-5
Molecular Formula	C24H38O6S
Molecular Weight	454.62 g/mol
Synonyms	11-Deoxy-11α-(2-Hydroxyethylthio)-PGE2 Methyl Ester; Methyl 11-Deoxy-11α-[(2-hydroxyethyl)thio]-9-oxoprosta-5,13-dien-1-oate; 11-Deoxy-11α-(2-hydroxyethylmercapto)-prostaglandin E2 methyl ester; PGE2 Methyl Ester Derivative; Prostaglandin E2 Methyl Ester Analog; 11α-(2-Hydroxyethylthio)-11-deoxy-PGE2 Me ester; 74412-44-5
EINECS	Contact for details

Quality Control

Our 11-Deoxy-11Alpha-(2-Hydroxyethylthio)-Prostaglandin E2 Methyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled temperature of -20°C or below to prevent oxidation and ensure long-term stability. The material is light-sensitive and easily oxidized; avoid exposure to air, moisture, and elevated temperatures.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.