Description

Cytochalasin H(2)B is a potent secondary metabolite belonging to the cytochalasin family of fungal-derived compounds. This product is valued for its specific biological activity as a microfilament-disrupting agent, making it a critical tool in cell biology and cytoskeleton research. It is primarily utilized by researchers and manufacturers in the life sciences, pharmaceutical development, and biotechnology sectors for studying cell motility, morphology, and intracellular transport mechanisms.

Application

• Cell Biology Research: As a specific inhibitor of actin polymerization, used to study cytoskeletal dynamics, cell division, and intracellular trafficking.
• Pharmaceutical R&D: Serves as a reference standard and a lead compound in the discovery of novel therapeutics targeting cellular motility and metastasis.
• Biochemical Assays: Employed in in vitro assays to investigate the role of actin filaments in various cellular processes and signaling pathways.
• Academic Research: A key reagent in university and institutional labs for fundamental research in cell physiology and microbiology.
• Toxicology Studies: Used to understand the mechanisms of mycotoxins and to develop countermeasures against fungal toxins.

Basic Information

Product Name	Cytochalasin H(2)B
CAS No.	74409-92-0
Molecular Formula	C29H37NO5
Molecular Weight	479.61 g/mol
Synonyms	Cytochalasin H2B; Cytochalasin H-2B; 7-Dehydro-19,20-dihydro-18-deoxycytochalasin H; [1S-(1α,2β,6β,7β,10β,11α,13α,14α,16E,18E,20S*)]-13-(Acetyloxy)-1,2,6,7,10,11,14,20-octahydro-20-hydroxy-2,16-dimethyl-11-(1-methylethenyl)-19-oxo-18-azacyclotetradeca[16,17-b]indole-1,14-dicarboxylic acid 1-methyl ester
EINECS	Contact for details

Quality Control

Our Cytochalasin H(2)B is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters. We adhere to relevant industry standards for fine chemicals and can provide material suitable for use as a reference standard.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a dry environment and allowed to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.