Description

Oxytocin, 1-α-Mercaptoacetic Acid-iso-Asn(5)- CAS NO 74221-74-2 is a synthetic analog of the neuropeptide hormone oxytocin, modified at the 1-position with a mercaptoacetic acid moiety and featuring an iso-asparagine substitution at position 5. This engineered structure is critical for research into receptor binding affinity, metabolic stability, and the development of novel therapeutic agents targeting the oxytocin pathway. It is an essential biochemical tool for pharmaceutical R&D, academic research, and biotechnology applications focused on neuroendocrinology, social behavior studies, and peptide drug discovery.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel oxytocin receptor agonists or antagonists.
• Neurobiological Studies: Used in vitro and in vivo to investigate the structure-activity relationship (SAR) of oxytocin analogs on central and peripheral nervous system functions.
• Peptide Chemistry & Biochemistry: A vital substrate for studying peptide stability, enzymatic degradation pathways, and the effects of specific amino acid modifications.
• Drug Discovery Platforms: Employed in high-throughput screening (HTS) assays to identify and validate new compounds that modulate the oxytocin receptor for potential therapeutic use.
• Academic & Clinical Research: Supports fundamental research into social bonding, stress response, lactation, and parturition mechanisms at a molecular level.

Basic Information

Product Name	Oxytocin, 1-α-Mercaptoacetic Acid-iso-Asn(5)- CAS NO 74221-74-2
CAS No.	74221-74-2
Molecular Formula	C₄₃H₆₆N₁₂O₁₂S₂
Molecular Weight	1007.2 g/mol
Synonyms	1-Mercaptoacetic acid-oxytocin (5-L-isoasparagine); [1-β-Mercaptopropionic acid, 5-L-isoasparagine]-oxytocin; 1-MPA-iso-Asn⁵-Oxytocin; Oxytocin (1-β-mercaptopropionic acid, 5-L-isoasparagine); Desamino-1-carba-iso-Asn⁵-oxytocin analog; Tocinoic acid-iso-Asn⁵ derivative; OT analog 74221-74-2
EINECS	Contact for details

Quality Control

Our Oxytocin, 1-α-Mercaptoacetic Acid-iso-Asn(5)- CAS NO 74221-74-2 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, MS for identity confirmation, and tests for related substances and residual solvents, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with full traceability are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0% (by amino acid analysis)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.