Description

3-Pyridinol, 2,4,5,6-Tetrafluoro- is a highly fluorinated pyridine derivative, a key building block in advanced organic synthesis. Its unique structure, featuring a hydroxyl group on a perfluorinated pyridine ring, makes it a critical intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate fluorine for enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of fluorinated drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used to create novel fluorinated pesticides and herbicides, where fluorine atoms improve lipophilicity and target binding.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized fluorinated ligands used in catalysis and material science.
• Advanced Material Research: Employed in the development of fluorinated liquid crystals, organic semiconductors, and polymers with unique electronic properties.
• Chemical Biology Probes: Utilized to create fluorinated analogs of biological molecules for metabolic pathway studies and imaging.
• Custom Synthesis and R&D: A valuable scaffold for contract research organizations (CROs) and academic institutions exploring new chemical entities.

Basic Information

Product Name	3-Pyridinol, 2,4,5,6-Tetrafluoro-
CAS No.	74199-51-2
Molecular Formula	C5H2F4NO
Molecular Weight	168.07 g/mol
Synonyms	2,4,5,6-Tetrafluoro-3-hydroxypyridine; 3-Hydroxy-2,4,5,6-tetrafluoropyridine; Tetrafluoro-3-pyridinol; 2,4,5,6-Tetrafluoropyridin-3-ol; 3-Pyridinol, tetrafluoro-; Perfluoropyridin-3-ol (common name); 3-Hydroxytetrafluoropyridine
EINECS	Contact for details

Quality Control

Our 3-Pyridinol, 2,4,5,6-Tetrafluoro- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.