Description

2-(Acetylamino)Indane-5-Sulfonyl Chloride is a specialized sulfonyl chloride derivative, a key reactive intermediate in advanced organic synthesis. Its molecular structure makes it a valuable building block for constructing complex molecules with specific functional properties. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing sulfonamide-based pharmacophores.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, or insecticides, where the indane-sulfonyl moiety can contribute to biological activity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers, coatings, or advanced materials with tailored properties.
• Chemical Biology Probe Development: Employed to create activity-based probes or affinity labels for studying enzyme function and protein interactions in biochemical research.
• Dye and Pigment Intermediate: Acts as a key component in the synthesis of specialized dyes, pigments, or optical brighteners.

Basic Information

Product Name	2-(Acetylamino)Indane-5-Sulfonyl Chloride
CAS No.	74124-92-8
Molecular Formula	C11H12ClNO3S
Molecular Weight	273.73 g/mol
Synonyms	5-(Chlorosulfonyl)-2-indanamine, N-acetyl-; 2-Acetamidoindane-5-sulfonyl chloride; N-[5-(Chlorosulfonyl)-2,3-dihydro-1H-inden-2-yl]acetamide; 2-Acetylaminoindane-5-sulfonyl chloride; 1H-Indene-5-sulfonyl chloride, 2-(acetylamino)-2,3-dihydro-; 2-Acetamido-2,3-dihydro-1H-indene-5-sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 2-(Acetylamino)Indane-5-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.