Description

9Alpha,11Alpha-Methylene-15S-Hydroxy-11A-Deoxy-11A-Methylene-Thromba-5Z,13E-Dien-1-Oic Acid is a high-purity synthetic prostaglandin analog, a key intermediate in advanced pharmaceutical research and development. This compound is valued for its structural complexity and precise stereochemistry, which are critical for developing novel therapeutic agents targeting specific biological pathways. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of new drug candidates, particularly in the fields of cardiovascular, inflammatory, and reproductive medicine.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel prostaglandin-based therapeutics.
• Biochemical Research: Used as a reference standard and active probe in studies of thromboxane and prostaglandin receptor pharmacology.
• Drug Discovery: Serves as a key precursor in medicinal chemistry programs aimed at developing new anti-inflammatory or vasoactive agents.
• Process Development: Employed in the scale-up and optimization of synthetic routes for complex bioactive molecules.
• Analytical Standard: Provides a high-purity benchmark for quality control and method validation in analytical laboratories.

Basic Information

Product Name	9Alpha,11Alpha-Methylene-15S-Hydroxy-11A-Deoxy-11A-Methylene-Thromba-5Z,13E-Dien-1-Oic Acid
CAS No.	74034-56-3
Molecular Formula	C22H32O4
Molecular Weight	360.49 g/mol
Synonyms	9,11-Methylene-15S-hydroxy-11-deoxy-11-methylene-thromba-5Z,13E-dien-1-oic acid; 9α,11α-Methylene-15S-hydroxy-11-deoxy-11-methylene-thromba-5Z,13E-dien-1-oic acid; 9,11-Methano-PGH2 analog; Thromboxane A2 analog intermediate; Prostaglandin H2 analog; 9,11-Epoxy-methano-PGH2 derivative; CAS 74034-56-3
EINECS	Contact for details

Quality Control

Our 9Alpha,11Alpha-Methylene-15S-Hydroxy-11A-Deoxy-11A-Methylene-Thromba-5Z,13E-Dien-1-Oic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the stringent requirements for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, assay, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	95.0% - 105.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.