Description

Acth, 2,4-Dinitro-5-Azidophenylsulfenyl- CAS NO 73905-66-5 is a specialized chemical reagent featuring a unique sulfenyl azide functional group. This compound is valued for its role as a photoactivatable crosslinking agent and a key intermediate in the synthesis of advanced materials and bioactive molecules. It is primarily sought by research and development teams in the pharmaceutical, bioconjugation, and polymer science industries for applications requiring precise, light-induced chemical modifications.

Application

• Photoaffinity Labeling: A critical reagent in biochemical research for covalently tagging and studying protein-ligand interactions and active sites upon UV light activation.
• Polymer Modification & Crosslinking: Used to introduce photo-reactive sites into polymer chains, enabling the development of light-curable coatings, adhesives, and advanced polymeric networks.
• Bioconjugation & Probe Synthesis: Serves as a versatile intermediate for attaching reporter molecules (e.g., fluorophores, biotin) to proteins, peptides, or other biomolecules for diagnostic and imaging applications.
• Organic Synthesis Intermediate: Employed in the preparation of complex heterocyclic compounds and other sulfur/nitrogen-containing derivatives for medicinal chemistry and material science.
• Surface Functionalization: Applied to modify material surfaces (e.g., gold, silicon) with reactive azide groups for subsequent "click chemistry" reactions to create biosensors or specialized coatings.

Basic Information

Product Name	Acth, 2,4-Dinitro-5-Azidophenylsulfenyl- CAS NO 73905-66-5
CAS No.	73905-66-5
Molecular Formula	C12H6N6O4S
Molecular Weight	330.28 g/mol
Synonyms	2,4-Dinitro-5-azidophenylsulfenyl chloride; 5-Azido-2,4-dinitrobenzenesulfenyl chloride; DNBS-Cl; ACTH (2,4-dinitro-5-azidophenylsulfenyl-); 1-Chlorosulfanyl-2-azido-4,6-dinitrobenzene; 5-Azido-2,4-dinitrobenzenesulfenylchloride; 2,4-Dinitro-5-azidobenzenesulfenyl chloride; Photoactivatable sulfenyl chloride reagent
EINECS	Contact for details

Quality Control

Our production of Acth, 2,4-Dinitro-5-Azidophenylsulfenyl- adheres to stringent quality protocols to ensure batch-to-batch consistency and high reactivity. Each lot is characterized by multiple analytical techniques including HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your research and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at temperatures between -20°C to -10°C for long-term stability. This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., argon or nitrogen) when not in use and handled in a controlled environment to minimize exposure to moisture and ambient light.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Solubility	Soluble in common organic solvents (e.g., DMF, DMSO, acetonitrile)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.