Description

16-Fluoromethyleneprostaglandin F2Alpha is a fluorinated analog of prostaglandin F2α, a key bioactive lipid mediator. This compound is valued for its enhanced metabolic stability and potent biological activity, making it a critical intermediate in advanced pharmaceutical research and development. It is primarily utilized by researchers and manufacturers in the life sciences sector for developing novel therapeutic agents and conducting detailed pharmacological studies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel prostaglandin-based drugs targeting ocular pressure, fertility, and inflammation.
• Biochemical Research: Used as a potent and selective agonist in studies of FP prostanoid receptor signaling pathways and function.
• Drug Discovery: Serves as a lead compound or reference standard in the development of new therapeutics with improved pharmacokinetic profiles.
• Metabolic Studies: Employed to investigate the structure-activity relationships (SAR) of prostaglandin analogs and their resistance to enzymatic degradation.
• Veterinary Medicine: Potential application in the development of treatments for animal reproductive health management.

Basic Information

Product Name	16-Fluoromethyleneprostaglandin F2Alpha
CAS No.	73885-87-7
Molecular Formula	C₂₁H₃₃FO₅
Molecular Weight	384.49 g/mol
Synonyms	16-Fluoromethylene-PGF2α; 16-Fluoro-PGF2α analog; 9α,11α,15S-Trihydroxy-16-fluoromethylene-5-cis,13-trans-prostadienoic Acid; 16-Fluoromethylene-prostaglandin F2 alpha; Fluprostenol analog; Prostaglandin F2α, 16-fluoromethylene-; 16-FM-PGF2α
EINECS	Contact for details

Quality Control

Our 16-Fluoromethyleneprostaglandin F2Alpha is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.