Description

Naltrexazone CAS NO 73674-86-9 is a specialized pharmaceutical intermediate and research chemical of significant interest in medicinal chemistry. Its primary value lies in its structural relationship to opioid antagonists, making it a critical building block for the development and synthesis of novel therapeutic agents. This compound is essential for pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers focused on neuropharmacology and addiction medicine.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of advanced opioid receptor antagonists and related pharmacologically active molecules.
• Medicinal Chemistry Research: Used as a reference standard and scaffold for structure-activity relationship (SAR) studies targeting the central nervous system.
• Biochemical Research: Employed in vitro studies to investigate ligand-receptor interactions at opioid receptors.
• Fine Chemical Synthesis: Serves as a high-purity building block for custom synthesis and contract manufacturing of specialized APIs.
• Reference Standard: Utilized in analytical laboratories for method development, validation, and quality control testing of related compounds.

Basic Information

Item	Detail
Product Name	Naltrexazone
CAS No.	73674-86-9
Molecular Formula	C20H23NO4
Molecular Weight	341.41 g/mol
Synonyms	Naltrexazone; 17-(Cyclopropylmethyl)-4,5α-epoxy-3,14-dihydroxymorphinan-6-one; 6-Oxo-naltrexone; Noroxymorphone cyclopropylmethyl ether; CP-45,634; (5α)-17-(Cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-one
EINECS	Contact for details

Quality Control

Our Naltrexazone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and tests for residual solvents and heavy metals. We provide full traceability and Certificates of Analysis (COA) are available upon request to ensure compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.