Description

4-Methyltamoxifen is a selective estrogen receptor modulator (SERM) and a key chemical intermediate in advanced pharmaceutical research and development. This compound is valued for its role in the synthesis of novel therapeutic agents targeting hormone-dependent conditions. It is primarily utilized by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in oncology and endocrinology research.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of tamoxifen analogs and related SERM compounds for therapeutic development.
• Biochemical Research: Used as a reference standard and active probe in studies of estrogen receptor (ER) signaling pathways and mechanisms of action.
• Medicinal Chemistry: Serves as a core scaffold for the design and optimization of new drug candidates with potential anti-cancer properties.
• Academic & Contract Research: Employed in university and CRO laboratories for investigating breast cancer therapeutics and hormone receptor biology.
• Process Development: Used in scaling up and optimizing synthetic routes for the production of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	4-Methyltamoxifen
CAS No.	73617-95-5
Molecular Formula	C26H29NO
Molecular Weight	371.52 g/mol
Synonyms	4-Methyltamoxifen; (Z)-4-Methyltamoxifen; trans-4-Methyltamoxifen; 1-[4-[2-(Dimethylamino)ethoxy]phenyl]-1,2-diphenyl-1-butene; 4-Methyl Tamoxifen; 4-Me-Tam; 4-MT; ICI 47699
EINECS	Contact for details

Quality Control

Our 4-Methyltamoxifen is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements of research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.