Description

5-Androsten-3Beta,17Beta-Diol-16,16,17-D3 is a high-purity, deuterium-labeled steroid derivative, specifically a stable isotope-labeled analog of androstenediol. This compound is of significant value as an internal standard in analytical chemistry, enabling precise quantification and method validation in complex biological matrices. It is primarily required by pharmaceutical research laboratories, contract research organizations (CROs), and diagnostic manufacturers for use in mass spectrometry-based assays, pharmacokinetic studies, and the development of clinical diagnostic tests.

Application

• Internal Standard for LC-MS/MS: Critical for accurate quantification of endogenous androstenediol and related steroids in bioanalytical methods.
• Metabolic Pathway Research: Used as a tracer to study steroidogenesis, hormone metabolism, and endocrine function in preclinical research.
• Clinical Diagnostics Development: Essential for calibrating assays in clinical laboratories for hormone level testing.
• Pharmaceutical R&D: Supports drug metabolism and pharmacokinetics (DMPK) studies for compounds affecting the endocrine system.
• Reference Standard: Serves as a certified reference material for quality control and method validation in regulated environments.
• Doping Control Analysis: Employed in sports anti-doping laboratories for the precise detection of prohibited anabolic agents.

Basic Information

Product Name	5-Androsten-3Beta,17Beta-Diol-16,16,17-D3
CAS No.	73609-45-7
Molecular Formula	C19H27D3O2
Molecular Weight	293.47 g/mol
Synonyms	Androst-5-ene-3β,17β-diol-16,16,17-d3; 3β,17β-Androstenediol-d3; 5-Androstenediol-d3; Androst-5-ene-3β,17β-diol (16,16,17-d3); 5-Androsten-3β,17β-diol-d3; Deuterated Androstenediol; Androstenediol Internal Standard; [16,16,17-2H3]-5-Androstene-3β,17β-diol
EINECS	Contact for details

Quality Control

Our deuterated steroid products are manufactured under strict quality control protocols to ensure the highest isotopic purity and chemical integrity. Each batch is characterized using advanced analytical techniques including NMR and High-Resolution Mass Spectrometry (HRMS). A comprehensive Certificate of Analysis (COA) is provided, detailing isotopic enrichment, chemical purity, and confirming identity. We support compliance with GMP and ISO 17034 guidelines for reference material producers.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term stability, storage at -20°C is recommended.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 98.0 atom % D
Chemical Purity	≥ 95.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.