Description

1-Deoxymannojirimycin Hydrochloride is a potent and selective inhibitor of class I α-mannosidases, enzymes critical to N-linked glycan processing. This high-purity biochemical is essential for researchers and manufacturers developing glycosylation inhibitors and studying metabolic pathways related to lysosomal storage disorders. It serves as a critical tool compound for pharmaceutical R&D, academic research in glycobiology, and the production of reference standards.

Application

• Glycobiology Research: Used as a specific inhibitor to study the role of α-mannosidases in N-glycan biosynthesis and processing within cellular systems.
• Pharmaceutical Development: Serves as a key intermediate or reference standard in the development of therapeutic agents targeting glycosylation-related diseases, such as certain cancers and viral infections.
• Enzyme Inhibition Studies: Employed in biochemical assays to characterize α-mannosidase activity and to screen for novel inhibitors in drug discovery platforms.
• Diagnostic Reagent Manufacturing: Utilized in the formulation of enzymatic assay kits for research and clinical diagnostics related to carbohydrate metabolism disorders.
• Academic & Industrial R&D: A fundamental tool for investigating endoplasmic reticulum-associated degradation (ERAD) and quality control of glycoprotein folding.

Basic Information

Product Name	1-Deoxymannojirimycin Hydrochloride
CAS No.	73465-43-7
Molecular Formula	C6H14ClNO4
Molecular Weight	199.63 g/mol
Synonyms	1,5-Dideoxy-1,5-imino-D-mannitol Hydrochloride; D-Mannojirimycin, 1-deoxy-, hydrochloride; (2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-triol Hydrochloride; Deoxymannojirimycin HCl; DMJ hydrochloride; α-Mannosidase Inhibitor; MDL 25,637
EINECS	Contact for details

Quality Control

Our 1-Deoxymannojirimycin Hydrochloride is manufactured under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing identity, purity, and specific test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.