Description

S(-)-Sch-23388 Hcl is a high-purity, enantiomerically pure chemical compound used as a selective dopamine D1 receptor antagonist in advanced research. This specificity makes it a critical tool for studying neurological pathways and receptor functions in both in vitro and in vivo models. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on neuroscience, neuropharmacology, and drug discovery.

Application

• Neuroscience Research: A key pharmacological tool for selectively blocking dopamine D1 receptors to study their role in behavior, cognition, and motor control.
• Drug Discovery & Development: Used in high-throughput screening and target validation assays for potential therapeutics targeting dopaminergic systems.
• Academic & Preclinical Studies: Essential for investigating the mechanisms of addiction, Parkinson's disease, schizophrenia, and other CNS disorders in laboratory settings.
• Biochemical Assays: Serves as a reference standard and active agent in receptor binding studies and functional cellular assays.
• Pharmacology Reference Material: Used to calibrate instruments and validate experimental models requiring a pure D1 antagonist.

Basic Information

Product Name	S(-)-Sch-23388 Hcl
CAS No.	73445-63-3
Molecular Formula	C17H18ClNO • HCl
Molecular Weight	324.25 g/mol
Synonyms	(5R)-8-Chloro-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1H-3-benzazepin-7-ol hydrochloride; (R)-(+)-8-Chloro-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1H-3-benzazepin-7-ol hydrochloride; SCH-23388 hydrochloride; (R)-SCH-23388 hydrochloride; S(-)-SCH 23388; Dopamine D1 receptor antagonist SCH-23388; Benzazepine D1 antagonist
EINECS	Contact for details

Quality Control

Every batch of S(-)-Sch-23388 Hcl is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We provide full traceability and Certificates of Analysis (COA) detailing purity, identity, and impurity profiles, ensuring consistency for critical research applications. Our quality commitment aligns with the standards expected for pharmacological reference materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.