Description

7-Hydroxy-5,11-Dioxotetranorprostane-1,16-Dioic Acid is a high-purity prostaglandin derivative and key synthetic intermediate of significant value in advanced pharmaceutical research and development. Its primary importance lies in its role as a critical building block for the synthesis of complex bioactive molecules, particularly those targeting inflammatory and metabolic pathways. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries who require reliable, high-quality intermediates for complex synthesis.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of advanced prostaglandin analogs and related therapeutic agents.
• Biochemical Research: Used as a reference standard or starting material in studies investigating eicosanoid metabolism, receptor binding, and signal transduction pathways.
• Process Chemistry: Serves as a key intermediate in the scale-up and optimization of manufacturing routes for prostaglandin-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to develop new chemical entities with modified biological activity.
• Fine Chemical Synthesis: Utilized for the preparation of specialized, high-value compounds for research and diagnostic applications.

Basic Information

Product Name	7-Hydroxy-5,11-Dioxotetranorprostane-1,16-Dioic Acid
CAS No.	73303-30-7
Molecular Formula	C18H26O7
Molecular Weight	354.40 g/mol
Synonyms	7-Hydroxy-5,11-dioxotetranorprostane-1,16-dioic acid; 7-Hydroxy-5,11-diketotetranorprostane-1,16-dioic acid; Tetranor PGDM; 7-Hydroxy-5,11-dioxo-tetranor-prostane-1,16-dioic acid; 1,16-Dioic acid, 7-hydroxy-5,11-dioxotetranorprostane-; PGDM metabolite; Prostaglandin D2 metabolite (7-Hydroxy-5,11-dioxotetranorprostane-1,16-dioic acid)
EINECS	Contact for details

Quality Control

Our 7-Hydroxy-5,11-Dioxotetranorprostane-1,16-Dioic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.